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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4633f20dbae803ba79379170bb2e5e5caa48eddfce0815ffbecda876df75ff4f' 
  AND token = 'Ywrqrm7H9xo+pvUfH4m/UiToZvCgMk1TdLQ4rzdIOkk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}