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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b5eaccc46d1fb9d013c8a322b0f20a5bd5ecc29432d7a3bad9733ee07d46ade' 
  AND token = 'W1cTKXPwYZAY+k+gEaFTnMKhd2LZeN1aj4qRLSGsIG0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}