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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d7d59506d3ad2dadb8832a44b4bbf4515cf506b563280763d51453cd7f5f57f' 
  AND token = 'Em1SZNM37NwG8AJqyF4BFy/FRog0CLEEI9+fUk3L9Jw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}