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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18c708f0b6410df59584f948d94991ae38d538b248f791d3c53bd3b84270e0b5' 
  AND token = '1tgu8LRL1fgf6wNhOqDYugyccUHPwPs4rcUfv98jTzw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}