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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ec1823555d150a1a04d68c58260a167b198b2c522a73b79c9d412d39b5553a1' 
  AND token = 'wE3A408+N2xEnlR6OC7+2euaW9ffa2dVBbfddi44cvM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}