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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a3740fb0497289283b6db1bc578f01c7fc5f38e7c64c971f7cdbe344f57a1bb' 
  AND token = 'gwicPTaDrs+RxpJow/t+iSQacZZIQhby781/oei9eOg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}