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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9326b0a3ab62b3f107cbce8462b38d035f4eb07de9c62df982c5692324bc5463' 
  AND token = 'iZg/x29oM5ddHnnl6RTOaSwEhfo2zLy2ciqymUFBgOg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}