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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fde0d0d21ac614e85aedde4d292f2455c974ac7ecb53224520480fea7104d6dd' 
  AND token = '/khfeMYlh4X6KdTvj8nuuSjPzQJE4FgQJO9kGi08uRs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}