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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c451d0013773058516c89aea4d8128a59a1515ecb825f2b0cbab72d4e262c479' 
  AND token = 'YJ73P89VX+szDWY5NP2CLyQQ1V22kBgaNGtpaKFTtes=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}