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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b205b2a2c8216ee51d6b13385c40ccc2b8ebc8d2bb67c0370278dee66db6986' 
  AND token = 'EGWrZuFiCgKrO8SwcdKwthqOUcw+i1isXmkcLNGy+0w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}