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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4cb7d27d8f630b0651158a2d8c01880fab2d64cd2fe497d6712e8fac3f66cb03' 
  AND token = 'lQkBdQ+Odw9dg9oWAYktjPfqDrts13NdwBwFkFfDNKY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}