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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '374b4eb2faab1f86765478c3a297027d0e7179bbcb5d4c2d39b3a620f01244e2' 
  AND token = '+t6tR8bpB19NQI/t3C2lMyEcqdwXg8NnRfOrbIhaUIE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}