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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0733997b4d9cb6680cfbf9a1bd2282853cc13e5ecfbbf9684d048391bf515b29' 
  AND token = 'oXqR/aLKDel1g6nHCJOjnd9LS6Umorkaj1qoVh4aICI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}