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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0cf51d8d94fc3af46cffca694c97757d4fe6831df2c9b0d65c3baa2408311845' 
  AND token = 'SEdy0VpYnI5EdhmH+eXdL/6N3qoLTden0g8QBBvVfAc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}