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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6133830eaedb3503fa6d52e61d3f0cf1b2e7fc19017eea3020d079a9984f0a18' 
  AND token = 'e0Hpz+7fWxrwQAkXkBK67effATLiRqccVaacNK7TLe0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}