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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51450546f9228f74bafe7435c4fe46a3482bc0940e74d1d61f653616de13825e' 
  AND token = 'o499SFJ1f10XMetKHdmb7trQjPM2MJozZPfVjdbfgCo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}