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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '97659f67e17916f12fc7da19e489dca22cadb82bb3ec7d78960d49a5e8f1a305' 
  AND token = 'SkT9UTHQwhZ24VkazANm9WgZqnMk89HI4JVGC2A3xf0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}