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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e25e74c37365cad14cb1900e6dfef8009c1d5226173f7f18af9948f19e9c606' 
  AND token = 'ZTRmim86z2a1zbIUtky15ErltQXbfng4gCteN5TbiYA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}