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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c9e5417ba4dbeb290d36c17695b475c933c7293490700facc1e9df7ea3e72a6f' 
  AND token = 'w+dhj7wS6YY8CAj1VcjyCJEF66Lf5FnlwXuiI/rS0zk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}