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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a0a9bc13a183a75b69075b30c542bdb28121925ec7758ea4f272e69bc93d1d8' 
  AND token = 'YqIzHeQ2Pf2jaXdprk+8LXe1cLjDtFX87JWAKgwDUgQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}