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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '433d39dbfc96b8b3451a9865de8644eb0aa4d046647527eebf1489ee5d6ac323' 
  AND token = 'cv52TJUbL2yJnEN7FcExW8xreyhWQuNUj7Dn5oOnMdI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}