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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4628fafcbc6e9db89a0c72fce22b136c42b8c64682cb091b4652b38851e08313' 
  AND token = 'PigWgni8he9a9cDbf9apbqAd/5RhE1hnPbxQGTtEGVs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}