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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e6867a7f4976d6c0c26dfff8bb82c50d3121dad51eb3662f72f52d3e45e80e1' 
  AND token = 'P0+Tc8f9zVqooJF+cNo2hxJS5eql0LffzGZHBpD03mo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}