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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '492a718e75c732e00672da8993e2766a0969a49f416b6ad65f51dedd4845a3b9' 
  AND token = 'wjfXZeRXntVdmrv26P7qaRgWPRDdiMKh7entLKXsj/M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}