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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '493d3341c79d1a918c7ec787ada1b7a580b66a937b9aa6156c4a96b01856c53c' 
  AND token = 'oM1GyIXrlA3Ypvd65sY6MyO6JSzHeR6qp5N0MEBQQhs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}