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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7748f328133afd5a607de6545ac25816a364d041a303dbf94bbd878fcf0d28d' 
  AND token = 'zyTAEBX76R7jE2z9fgv7MPFD8m+HJRuM9FAGB2ULiAI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}