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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a76d84c3da529adc12a682fb6da89215b7a3208840fd19df96e1f8563c799a55' 
  AND token = 'QdLD049Y1nRLPeTcpWAWnoSsWpcLRhIlW0eSgYWOWbM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}