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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '149e20d77dfde98c5a1fc6800317d9b63212f449a2c81e02588b463945ff1eba' 
  AND token = 'IEjRCFizcRNVTk2w9lUj2Srx57gKkhAKm+I5seSF0kA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}