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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '69c95582ca654fdadd439403b7261b753a85911206cd2b189e2e6a38aa168d63' 
  AND token = '78DY+bdkMq3cV3PxBz2xrhzpWltr2zUfIdAkTMw2P7U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}