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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a37aa7d378439711f5ea361a04cc13de4bf998f95964fc9540aca1e258364fd1' 
  AND token = 'F+69SyLG8lDob0/eXCmCNZ9tX+6mkSrHMZ3IPldIbGs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}