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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0afdc3419e637fc8a82c0a54fd55a957cacc45d80573da41364c2b61ddb3946b' 
  AND token = '8IPiAoWPpQG5hlB7bT47cLg2jO7DbRheEYeJsn3IeCY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}