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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a46a66e7901a1b3a887858eab8f3b5b66ff44c633ec0efd3ecaf4e91a4a7667' 
  AND token = 'Ejqyp1PH6K7dJPmJuKYeBl6+BhEgT05pvfRTC4sH2XQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}