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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cd643efc3c1864f2f7494638a5e8c882e2d8b0f5c1330694e1bbac3b123a605' 
  AND token = 'M8KdmUy1eCebIJoZP01vWekWkuwxb13J0uVk7yE1pCY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}