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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d864a269e7f91662386e3d6a790d38d9eb801f2aea6af0229bd5e19b37b6e6c' 
  AND token = 'nRIBu2ZNG3Hx9QOzbKoFwpR0EtmGtg3QoNCGiVZqdAk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}