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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e9fdef5f28fd6a57c293edcd0a7840f7a7b39fdae664be043899fcce308a461' 
  AND token = 'teHIkEGCuRh5dunv5MmL4cH3AbeS3qGcRLAr6l480Sw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}