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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61194de25b99eeb5730a34a81a4cb8af5208772ef12237ecdf2022a6426f3a50' 
  AND token = 'vkWD9B3xA3YbrrTx+DmLNOFINdurq0Md9EvUq2lb70g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}