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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ede1b1281c6655647551c0f38d1e9a9cb0487c5b25d98921cd5683948a307b42' 
  AND token = 'M2j/KnErB56bxmLfsUgiKibcdZUzA/kX2CWvNqlf0jA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}