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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4868b3823594884f03a32c4e8bacce6101ade9924766bca612b29e09642dd4a1' 
  AND token = 'O4Q10IAe6Vygr6pdWRtpGsqfMi6t7FJdA3fKgE6DMgE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}