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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8161ec41916e2ff9c47c5eb99624dc7232005e00208c1ecde08005850ca24224' 
  AND token = 'QnDJnVYYs66rKFawqiE180r6vkAExC6HB72ewOhQ7tI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}