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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd197c9cdddcfee22257c3f54be2dffa505b4a6a518fb56c15e2cbb41ffc2398' 
  AND token = '2avhIS2a5TEQBC7laCdt9T7Dt3GTQtrh6m8z4e/SEZg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}