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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25305eb8c875c330a29ee71b30b67f21f684e945cf2fde9db76d43d1dcf809c6' 
  AND token = 'sD0tZXa4hIZlE+XZ0+LwG+7ZJck596JRPQeNBHI+pPs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}