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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb7c5e8984c005193aece599140a709286d576812656b43d9c19e2e683a0da67' 
  AND token = 'sUIMXnJfcAmyT7hDJ+q3zzDAOi4JG5ogc6nJIfTH+sM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}