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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e460fedc62a6cf3a287bf054ed9cb2e2d821f93e67005e6df40060ade3a2a254' 
  AND token = 'acVcP/WjA6BkKaBGDgXr8123imhjQoVb24geFOyLad0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}