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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80521a01e8bfb7981f192e793edf8cace1da6e87cf9efed772e17eb51e2eb1c4' 
  AND token = 'nWAAxE6pF2WL35hsIHNZh34nDyw2Ckes/cCGe/zOgUM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}