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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe18e0db94d82a74837032254d8fa245648b265ac9802e6b7231cb04fda69e2d' 
  AND token = 'dYBrme3PV2EX5hLDaJgWD0+aXwmrVWI841V7ZMrFtdw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}