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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c38f9bb172e6164bedc0f1f4f1c477283e3c27c7f961a12366d9b0ecb66e9f06' 
  AND token = 'Pww0ay+D8R+PyTOkBypFeuXe2LgbG6iMWjCuVCqbgNY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}