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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2567b0596ea2a50fe486518c89a37b338be04af709dea0a546b5a0909a7b8f98' 
  AND token = '0V7qTwt1yJLI9gxqUUSygU9M4ke1cwt9rmZNwfe9LeQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}