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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8070a03cde7e3cd0e13e28c8003315b139520bd26c3341f8565162eade5d4ff7' 
  AND token = 'ddrz33/Q4jY1Rt8drDhGMBFuCy00Jie+ig5n7Kqd/II=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}