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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9e2ea7ab3635a585a969fb4fb9b40eee7ed6c29bca2d61ceda41ddd899a8016' 
  AND token = 'SX+cE3M05d29sE5/lOz366qur24XikWhYdDsOWVqRn8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}