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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6c6e87378de308f3f8cda8707c3b38e8473f1f3b1ae1bd531d1610cb0639b03' 
  AND token = 'p79voFfezNMPLnikw1F2CNqb3lmks/6170Q6zdekNoM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}